Forensic Toxicology Expert Witness

Lyle W. Hayes Ph.D., DABCC

    Toxicologist with College and University Teaching Experience in Chemistry and Life and Medical Sciences

Dr. Lyle Hayes is a New York State Certified Forensic Toxicologist with extensive experience in drugs of abuse testing as a New York State Department of Health Certified Lab Director and Certifying Scientist. He has extensive teaching experience at the undergraduate and graduate levels in chemistry, toxicology, biochemistry, and clinical chemistry.

Dr. Lyle Hayes has been practicing in the field of Forensic Toxicology for 30 years. He is an NYSDOH Board Certified Laboratory Director, Forensic Toxicology Diplomat within the American Board of Clinical Chemistry, and a full member in the Society of Forensic Toxicology. He received his Ph.D. in Biochemistry and Biophysics from Oregon State University, as well as studying as a Clinical Resident in Clinical Chemistry and Toxicology at the Oregon Health Sciences University.

He is qualified to provide a comprehensive analysis and evaluation of the data used in your case. This includes evaluating test validity, testing for interferences and false positives, chain of custody, qualitative and quantitative analysis, and interpreting the results. If you have any further questions, please reach out to him via his contact page.

A comprehensive CV can be downloaded below. References available upon request.

A brief summary of his services can be found here.


NYSDOH Laboratory Director Certificate of Qualification, Forensic Toxicology

Diplomat, American Board of Clinical Chemistry.

Full Member, Society of Forensic Toxicology


 B.A. Chemistry – Colorado College          

 Ph.D. Biochemistry/Biophysics – Oregon State University   

Clinical Resident, Clinical Chemistry and Toxicology – Oregon Health Sciences University

Courses taught at an undergraduate level: Introductory Chemistry, Organic Chemistry, General Biochemistry, Molecular Biochemistry, Clinical Chemistry, Clinical Instrumentation, Special Chemistry (Clinical), Biochemistry Seminar, History of Disease, History of Science, Human Environmental Disease.

Courses taught at a graduate level: Biochemistry, Clinical Pathology Seminar, Pathophysiology, Serum Proteins, Molecular Biology.


Laboratory Director: Startnew Medical PC, Wappingers Falls, New York. May 2015-2019.

Laboratory Director: Restoration Sport and Spine Care  Dobbs Ferry, NY. March 2016-present.

Director, Saratoga Laboratories. 2006-2009

Maintain laboratory certification and compliance with NYSHOH inspection and proficiency program for urine and hair drugs of abuse testing. Certify all results and maintain quality assurance and control. Supervise laboratory personnel and operations. Develop, validate, and implement analytic methods on GC/MS, GC/MS/MS, and LC/MS/MS instrumentation.

Laboratory Director, Northeastern Toxicology Laboratory:  Forensic Toxicologist. 1996-2006.

Established and maintained laboratory certification and compliance with NYSHOH inspection and proficiency program. Developed, validated, and implemented urine drugs of abuse EMIT screening and confirmation methodology with GC/MS.  Developed, validated, and implemented Hair testing for Amphetamines, Opiates, Cocaine metabolites, Phencyclidine, and THCA and a highly sensitive Ethylglucuronide method.

Chemistry Supervisor, Leonard Hospital and Seaton Health System, Troy, NY.  1993-1996.

Supervised chemistry and toxicology section of laboratory, including quality control and quality assurance and NYSDOH proficiency compliance. 

Clinical Chemist, Dept. Clinical Pathology and Laboratory Medicine, Albany Medical Center, Albany, NY.

Responsible for supervision of stat lab, blood gas section, satellite, and decentralized testing.

Clinical Chemistry Fellow, Dept. Clinical Pathology and Laboratory Medicine, Albany Medical Center, Albany, NY.

Visiting Professor of Chemistry, Division of Natural Sciences, Bennington College, Bennington, Vermont.

Taught undergraduate organic and general chemistry, with labs.

Assistant Professor, Clinical Chemistry, Department of Health Sciences, University of Wisconsin-Milwaukee.

Taught clinical chemistry and toxicology for medical technology students.  Supervised Graduate Program.

Clinical Chemistry Resident, Clinical Pathology and Toxicology, School of Medicine, Oregon Health Sciences University.

Assistant Professor,  Biochemistry Department, University of Massachusetts, Amherst, MA.  

Research Associate,  Biochemistry Department, University of Massachusetts, Amherst, MA.

Research Associate, Biochemistry Department, Eunice Kennedy Shriver Center for Mental Retardation and Harvard Medical School. 

Recently Invited Presentations and Seminars:
  • “Environmental Sources of Human Disease”.  Environmental Sciences, Skidmore College, Spring 2003
  • “Chromatography of Natural Substances”  Laboratory and Lecture, Science Institute for Girls. Skidmore College, July 1999 -2003.
  • “Pharmacogenetics and Medicine of the Future”. Elder Hostel Lecture Series, Skidmore College, September 2001.
  • “Human Environmental Toxicology—an Introduction” Environmental Sciences, Skidmore College, December 2001
  • “Fad Diets in the US-—A Biochemist’s View of What Works and Why”. Sciences Division, Adirondack Community College, May 2001.
  • “Antioxidants and nutrition in diet and supplements in the elderly” Elder Hostel Lecture Series, Skidmore College, September 2000.
  • “Drug Interactions in a Geriatric Population”  Elder Hostel Lecture Series, Skidmore College, September 1999.

Nominated by Medical Technology students for “Golden Apple” Award for Outstanding Teacher in School of Allied Health Professions, University of Wisconsin, Milwaukee

Nominated by students for Distinguished University Professor, University of Massachusetts, Amherst.

Received merit award for teaching excellence, University of Massachusetts.  Special teaching award by faculty.

NDEA Predoctoral Fellow, Oregon State University, 1966-1968.

Predoctoral Fellowship, Dept. Biochemistry and Biophysics, Oregon State University.

Awarded tuition scholarship, Colorado College.

Grants Obtained:

1988-1990 “Vascular Damage and Angiotensin-converting Enzyme”  NIH AREA Award, National Heart, Lung and Blood Institute, $72,000.

1987-1988 “Serum Forms of Angiotensin-converting Enzyme in Diagnosis and Disease”  Graduate Council Award, University of Wisconsin- Milwaukee $9600.

1982-1983 “Metabolism of Angiotensin-converting Enzyme in Endothelial Cells” NIH Biomedical Research Grant. 

1981-82 “Purification of Angiotensin-converting Enzyme from Cultured Endothelial Cells” NIH Biomedical Research grant.


LW Hayes et al.,  Ethylglucuronide in Urine by LC-MS/MS with Human Excretion Profiles Following Dermal and Oral Ethanol Use, Society of Forensic Toxicology Abstracts, 2007, p. S25

Rosano T, Swift T and Hayes L.  Advances in catecholamine and metabolite measurement for the diagnosis of pheochromocytoma, a review.  Clinical Chemistry, 37:1854-67, 1991

Rosano T, Hayes L, Dybas M, Nazeer T, Ross J.  Evaluation of an immunoradiometric assay for cathepsin  D concentration in breast and endometrial tumors. (Abstract) Clinical Chemistry, 37:1055, 1991

Otvos J, Hayes L, Jeyarajah E, Freedman D, Janjan N.  Relationship between the proton nuclear magnetic resonance properties of plasma lipoproteins and cancer. Clinical Chemistry, 37: 369-376, 1991.

Hayes L, Krasseldt W, Mueggler P,  Concentrations of codeine and morphine in serum and urine after ingestion of poppy seeds. Clinical Chemistry, 33:806, 1987. 

Hayes L, Swanson JR,  Elevated ammonia results due to bacterial contamination of aca tubing.  Clinical Chemistry, 30:1882, 1984.

Hayes L,  Rapid partial purification of angiotensin-converting enzyme from human plasma- preliminary report. Clinical Chemistry, 30:1061, 1984. 

Ching SF, Hayes L, Slakey LL,  Angiotensin-converting enzyme in cultured endothelial cells.  Synthesis, degradation and transfer to culture medium.  Atherosclerosis 3:581-588, 1983.